Using large scale porcine genome sequence information to find the underlying mutations associated with chromosome 17 QTL for meat quality. | Ramos, A. M., Hu, Z. L., Humphray, S., Rogers, J., Reecy, J. M., Rothschild, M. F. | Proceedings of the 8th World Congress on Genetics Applied to Livestock Production, Belo Horizonte, Minas Gerais, Brazil, 13-18 August, 2006

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Title: Using large scale porcine genome sequence information to find the underlying mutations associated with chromosome 17 QTL for meat quality.
Personal Authors: Ramos, A. M., Hu, Z. L., Humphray, S., Rogers, J., Reecy, J. M., Rothschild, M. F.
Author Affiliation: Department of Animal Science, Iowa State University, Ames, IA 50614, USA.
Editors: No editors
Document Title: Proceedings of the 8th World Congress on Genetics Applied to Livestock Production, Belo Horizonte, Minas Gerais, Brazil, 13-18 August, 2006

Abstract:

To efficiently improve pork production, causative mutations underlying QTL need to be identified. Several meat quality QTL were identified on SSC17. Fine mapping of the QTL region was achieved by adding 25 gene markers to the linkage map. Linkage disequilibrium association analyses, together with a QTL segment analysis allowed the identification of the chromosome region likely to contain the causative mutations responsible for the observed QTL. A BAC clone tile path spanning 8.5 MB on SSC17 was selected and sequenced. High quality finished sequence information facilitated the search for mutations and candidate genes.

Publisher: Instituto Prociência

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